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Elevated AST and ALT may signify liver injury so calling them “liver function tests” is a bit of a misnomer. The highest levels of aspartate aminotransferase (AST) are present in liver, cardiac tissue, and skeletal muscle, with smaller amounts present in the kidneys, pancreas, and erythrocytes. Alanine aminotransferase (ALT), however, is predominantly present in the liver. 🫀🫁🧠
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