"The importance of deoxyribonucleic acid (DNA) within living cells is undisputed" (Watson & Crick, 1953). This opening sentence of James Watson and Francis Crick's second major paper, published ...

The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

Research showed that a regulatory protein of chromosome structure (cohesin) is essential for proper maintenance of gene expression in the developing brain. Reduced cohesin impaired development of ...

In a leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful new artificial intelligence tool that can predict the 3D shape of ...

In a report published in the Proceedings of the National Academy of Sciences, researchers working at Florida State University (FSU), Baylor College of Medicine and the Broad Institute of Harvard and ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During mitosis, centromeres serve as assembly sites for complex protein ...

Each human cell contains 23 pairs of chromosomes that carry DNA within their nucleus. The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the ...

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have mapped out the molecular structure of a key part of our chromosomes called telomeres, which play a pivotal part in ...

Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...

Researchers centered at Japan's National Institute for Physiological Sciences reveal details of the structure of compacted DNA transiently formed at the time of cell division in cyanobacteria.