The accuracy of transcription processes varies widely among species, across cell types and within distinct regions of the genome, with profound consequences for health and disease.DNA transcription is ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...

A bacterial protein helps to stop transcription -- the process of making RNA copies of DNA to carry out the functions of the cell -- by causing the cellular machinery that transcribes the DNA to pause ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

A team of physicists working at the intersection of theory and experiment are shedding new light on the “teamwork” of molecular motors—called RNA polymerases (RNAPs)—that mediate DNA transcription.

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and epigenetic state. By analyzing thousands of sequences, the method showed that ...

Some things just go together like “rock and roll” and “fish and chips” or, in molecular biology, “transcription factors” and the “nearby genes they regulate.” The standard, simplified story goes like ...