DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH When cells in the human body divide, they must first make accurate copies of their DNA. The DNA ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

DNA replication is a tightly controlled process that copies the genetic code, allowing its instructions to be conveyed from one generation of cells to the next. In diseases like cancer, these ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...

How an enzyme involved in DNA repair becomes vital to the survival of certain cancers has been identified by scientists, paving the way for clinical trials evaluating the effects of blocking this ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, ...