AFM is a scanning probe microscopic instrument that consists of a force-sensing microcantilever, a laser source, a piezoelectric scanner and a photodiode detector (Figure 1A). During AFM imaging, the ...

Thought LeaderProf. Dr. Kristina Kusche-VihrogHead of Department, Institute of PhysiologyUniversity of Lübeck In this interview with News Medical Life Sciences, Prof. Dr. Kristina Kusche-Vihrog, head ...

New model extracts stiffness and fluidity from AFM data in minutes, enabling fast, accurate mechanical characterization of living cells at single-cell resolution. (Nanowerk Spotlight) Cells are not ...

Recognition of the crucial role that nanomechanical properties play in the structure and function of biological systems is growing steadily. Atomic force microscopy (AFM), a high-resolution surface ...

(Nanowerk News) Membrane rafts are nanometer-scale structures rich in cholesterol and sphingolipids, believed to serve as vital platforms for cell signaling, viral entry, and cancer metastasis. Since ...

Using localized force-distance curves from AFM, a deep neural network was trained and biologically validated to predict and accurately distinguish macrophage polarization states, including complex ...

First invented in 1985 by IBM in Zurich, Atomic Force Microscopy (AFM) is a scanning probe technique for imaging. It involves a nanoscopic tip attached to a microscopic, flexible cantilever, which is ...

(a) A scanning electron microscope (SEM) image of the nanoneedle probe used for the measurements. (b) Elasticity map of a 1 µm × 1 µm area on the nuclear surface, showing the change in elasticity ...

Anyone who has ever taken the time to critically examine a walnut knows that a two-dimensional photograph fails in many respects to truly convey the unique features--the nicks, crannies, valleys, and ...

ViViD-AFM could become a kind of "window" into the busy life of cells. It may help researchers watch how different shapes of flu viruses attach and enter, how cells release tiny packages called ...