Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Researchers identify the anterior insula as the brain region responsible for biasing decisions toward alcohol over social rewards in addiction.

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, new research finds. Michigan State University scientists have found that ...

Addiction has causes that are neurobiological, psychological and structural. Treating these drivers is as important as managing the initial withdrawal. Medically managed withdrawal does not restore ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Within the brain, chemical neurotransmitters like dopamine and norepinephrine regulate mood, emotions and many physiological and behavioral processes. Their imbalance can contribute to anxiety, ...

As our understanding of the neurobiology of addiction evolves, so do opportunities to develop more precise, brain-based interventions for co-occurring disorders. In our free webinar, “Advancing ...

Addiction decreases the brain’s ability to experience natural, healthy pleasure, driving increased cravings and compulsive substance use. But can this brain deficit be healed? New research from my lab ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...